Effects of Lipid Regulation Using Raw and Processed Radix Polygoni Multiflori in Rats Fed a High-Fat Diet
Table 4
Low density lipoprotein cholesterol (LDL-C) contents in blood samples.
LDL
0D
6D
18D
24D
30D
42D
A
22.33 ± 7.896
15.63 ± 4.228
28.45 ± 8.157
23.03 ± 3.350
16.94 ± 3.410
16.28 ± 3.567
B
26.23 ± 7.143
68.03 ± 24.60***
67.22 ± 13.45***
83.22 ± 21.49***
88.98 ± 32.26***
98.80 ± 35.21***
C
23.24 ± 6.831
51.57 ± 14.85***
70.48 ± 17.22***
89.36 ± 44.32***
114.1 ± 62.90***
92.35 ± 52.31***
D
18.56 ± 5.616
57.10 ± 17.34***
49.71 ± 14.07***, ##
69.78 ± 20.54***
88.17 ± 19.97***
80.05 ± 29.15***
E
21.98 ± 3.974
47.85 ± 17.38***, #
51.16 ± 9.723***, ##
60.05 ± 21.35***, #
98.18 ± 38.69***
74.29 ± 29.43***
F
19.76 ± 2.608
42.43 ± 16.61***, ##
50.66 ± 12.67***, ##,†
76.53 ± 43.37***
87.61 ± 48.40***
73.00 ± 32.86***
G
26.94 ± 6.340††
36.67 ± 13.89***, ###,††
47.81 ± 14.72***, ##
109.1 ± 44.91***,†
97.41 ± 40.59***
70.91 ± 63.17*
H
23.69 ± 3.758
57.83 ± 17.86***
42.15 ± 21.41##
125.0 ± 41.28***, ##,†††
98.78 ± 49.10***
81.14 ± 37.11***
I
19.82 ± 8.215
41.70 ± 13.06***, ##
58.39 ± 17.87***
125.3 ± 48.83***, #
83.46 ± 39.26***
61.13 ± 39.13**, #
J
18.98 ± 13.67
30.55 ± 11.18***, ###
45.82 ± 8.996***, ###
88.52 ± 19.35***
113.9 ± 53.11***
64.00 ± 35.28***
Low density lipoprotein cholesterol (LDL-C) contents were assayed by assay kits as described in the text. Values were mean ± SD (n = 12) and expressed in mg/dL. The * indicates a significant difference compared with control group, *P < 0.05, **P < 0.01, ***P < 0.001. The # indicates a significant difference compared with model group, #P < 0.05, ##P < 0.01, ###P < 0.001. The † indicates a significant difference compared with PMR group (same dosage level, F compared with C, G compared to D, H compared to E), †P < 0.05, ††P < 0.01, †††P < 0.001.
