Table 4: Effects of KBG on various parameters in group A .

PeriodWeek 0Week 4 -valuea -valueb

BMI (kg/m2)KBG 0.3362 0.6182
Control 0.5916
Waist circumference (cm)KBG 0.6699 0.9871
Control 0.8962
SBP (mmHg)KBG 0.6820 0.9476
Control 0.5591
DBP (mmHg)KBG 0.3790 0.4292
Control 0.3028
L_RHIKBG 0.0231* 0.0085**
Control 0.1834
TG (mg/dL)KBG 0.7791 0.5937
Control 0.5277
HDL-cholesterol (mg/dL)KBG 0.8341 0.6859
Control 0.8432
LDL-cholesterol (mg/dL)KBG 0.2268 0.0715
Control 0.1422
NEFA (μEq/L)KBG 0.0306* 0.0004**
Control 0.0028**
FPG (mg/dL)KBG 0.3768 0.2550
Control 0.7477
IRI (μU/mL)KBG 0.0593 0.1223
Control 0.5777
HOMA-IRKBG 0.2001 0.3213
Control 0.4815
Creatinine (mg/dL)KBG 0.5742 1.0000
Control 0.9734
hs-CRP (mg/dL)KBG 0.1962 0.2681
Control 0.0423*
MDA (nmol/mL)KBG 0.0007** 0.5068
Control 0.3444
sVCAM-1 (ng/mL)KBG 0.0121* 0.2791
Control 0.7389

KBG: keishibukuryogan; BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; L_RHI, natural logarithmic scaled reactive hyperemia; TG: triglyceride; HDL: high-density lipoprotein; LDL: low-density lipoprotein; NEFA: nonesterified fatty acid; FPG: fasting plasma glucose; IRI: immunoreactive insulin; HOMA-IR: homeostasis model assessment as an index of insulin resistance; hs-CRP: high-sensitive C-reactive protein; MDA: malondialdehyde; sVCAM-1: soluble vascular cell adhesion molecule 1.
aComparison between week 0 and week 4 by Wilcoxon signed-rank test.
bComparison of 4-week changes between KBG-treatment period and control period by MANOVA test.
Data are expressed as mean ± S.E., , .