Table 5: Effects of KBG on various parameters in group B .

PeriodWeek 0Week 4 -valuea -valueb

BMI (kg/m2)Control 0.4477 0.3443
KBG 0.7660
Waist circumference (cm)Control 0.9129 0.8807
KBG 0.8125
SBP (mmHg)Control 0.4676 0.0808
KBG 0.0037**
DBP (mmHg)Control 0.5524 0.7949
KBG 0.1567
L_RHIControl 0.2870 0.1751
KBG 0.0074**
TG (mg/dL)Control 0.9750 0.7320
KBG 0.9251
HDL-cholesterol (mg/dL)Control 0.0718 0.3085
KBG 0.4357
LDL-cholesterol (mg/dL)Control 0.1619 0.7604
KBG 0.5393
NEFA (μEq/L)Control 0.1289 0.9939
KBG 0.0312*
FPG (mg/dL)Control 0.0881 0.6065
KBG 0.1706
IRI (μU/mL)Control 0.1525 0.2374
KBG 0.6260
HOMA-IRControl 0.1342 0.2206
KBG 0.8140
Creatinine (mg/dL)Control 1.0000 0.4789
KBG 0.7539
hs-CRP (mg/dL)Control 0.4895 0.4382
KBG 0.8877
MDA (nmol/mL)Control 0.6747 0.0464*
KBG <0.0001**
sVCAM-1 (ng/mL)Control 0.4684 0.3898
KBG 0.3021

KBG: keishibukuryogan; BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; L_RHI: natural logarithmic scaled reactive hyperemia; TG: triglyceride; HDL: high-density lipoprotein; LDL: low-density lipoprotein; NEFA, nonesterified fatty acid; FPG: fasting plasma glucose; IRI: immunoreactive insulin; HOMA-IR: homeostasis model assessment as an index of insulin resistance; hs-CRP: high-sensitive C-reactive protein; MDA: malondialdehyde; sVCAM-1: soluble vascular cell adhesion molecule 1.
aComparison between week 0 and week 4 by Wilcoxon matched-pairs signed-ranks test.
bComparison of 4-week changes between control period and KBG-treatment period by MANOVA test.
Data are expressed as mean ± S.E., , .