Berberine Improves Insulin Sensitivity by Inhibiting Fat Store and Adjusting Adipokines Profile in Human Preadipocytes and Metabolic Syndrome Patients

<table>Effect of berberine on PPAR<i>γ</i>2, lipoprotein lipase, C/EBP<i>α</i>, leptin, and adiponectin mRNA expression in differentiated preadipocytes analyzed using RT-PCR. (a) Digital photos of PCR products in agarose gel. Lane 1: control group, lane 2: 10 <i>μ</i>M berberine, lane M: DNA markers. (b) Results are expressed as the ratio between the intensity of band corresponding to target gene versus that to <i>β</i>-actin, representing the mean ± SEM of the three separate experiments in triplicate. *<svg height="11.375" id="M11" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>, compared to control.</table>

Evidence-Based Complementary and Alternative Medicine

fig4

Figure 4

Figure 4: Berberine Improves Insulin Sensitivity by Inhibiting Fat Store and Adjusting Adipokines Profile in Human Preadipocytes and Metabolic Syndrome Patients 

Figure 4 | Berberine Improves Insulin Sensitivity by Inhibiting Fat Store and Adjusting Adipokines Profile in Human Preadipocytes and Metabolic Syndrome Patients 