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Evidence-Based Complementary and Alternative Medicine
Volume 2012 (2012), Article ID 364604, 28 pages
http://dx.doi.org/10.1155/2012/364604
Review Article

Potential Antiosteoporotic Agents from Plants: A Comprehensive Review

1Department of Pharmacognosy, School of Pharmacy, Second Military Medical University, Shanghai 200433, China
2Department of Pharmacy, Fujian University of Traditional Chinese Medicine, Fuzhou 350108, China
3School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Byrom Street, Liverpool L3 3AF, UK

Received 10 August 2012; Accepted 30 October 2012

Academic Editor: Olumayokun A. Olajide

Copyright © 2012 Min Jia et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Osteoporosis is a major health hazard and is a disease of old age; it is a silent epidemic affecting more than 200 million people worldwide in recent years. Based on a large number of chemical and pharmacological research many plants and their compounds have been shown to possess antiosteoporosis activity. This paper reviews the medicinal plants displaying antiosteoporosis properties including their origin, active constituents, and pharmacological data. The plants reported here are the ones which are commonly used in traditional medical systems and have demonstrated clinical effectiveness against osteoporosis. Although many plants have the potential to prevent and treat osteoporosis, so far, only a fraction of these plants have been thoroughly investigated for their physiological and pharmacological properties including their mechanism of action. An attempt should be made to highlight plant species with possible antiosteoporosis properties and they should be investigated further to help with future drug development for treating this disease.