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Evidence-Based Complementary and Alternative Medicine
Volume 2012 (2012), Article ID 371273, 10 pages
http://dx.doi.org/10.1155/2012/371273
Research Article

Balanophora spicata and Lupeol Acetate Possess Antinociceptive and Anti-Inflammatory Activities In Vivo and In Vitro

1Department of Pharmacology, China Medical University, No. 91 Hsueh-Shih Road, Taichung 40402, Taiwan
2Department of Pharmacy, China Medical University Hospital, Taichung 40427, Taiwan
3College of Pharmacy, China Medical University, Taichung 40402, Taiwan
4Chinese Medicine Research and Development Center, China Medical University Hospital, Taichung 40427, Taiwan
5Department of Chemistry, National Cheng Kung University, Tainan 70101, Taiwan
6School of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, China Medical University, Taichung 40402, Taiwan

Received 3 May 2012; Revised 6 October 2012; Accepted 9 October 2012

Academic Editor: Ke Ren

Copyright © 2012 Yuh-Fung Chen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. N. Y. Chiu and K. H. Chang, The Illustrated Medicinal Plants of Taiwan, vol. 2, Southern Materials Center, Taipei, Taiwan, 1986.
  2. X. K. Liu, Z. R. Li, M. H. Qiu, and R. L. Nie, “Triterpene constituents from Balanophora indica,” Acta Botanica Yunnanica, vol. 20, no. 3, pp. 369–373, 1998.
  3. Z. Dai, F. Wang, G. L. Wang, and R. C. Lin, “Studies on chemical constituents of Balanophora spicata,” Zhongguo Zhongyao Zazhi, vol. 31, no. 21, pp. 1798–1800, 2006. View at Scopus
  4. G. M. She, Y. J. Zhang, and C. R. Yang, “Phenolic constituents from Balanophora laxiflora with DPPH radical-scavenging activity,” Chemistry and Biodiversity, vol. 6, no. 6, pp. 875–880, 2009. View at Publisher · View at Google Scholar · View at Scopus
  5. W. F. Chiou, C. C. Shen, and L. C. Lin, “Anti-inflammatory principles from balanophora laxiflora,” Journal of Food and Drug Analysis, vol. 19, no. 4, pp. 502–508, 2011.
  6. C. R. Wu, Y. C. Hseu, J. C. Lien, L. W. Lin, Y. T. Lin, and H. Ching, “Triterpenoid contents and anti-inflammatory properties of the methanol extracts of Ligustrum species leaves,” Molecules, vol. 16, no. 1, pp. 1–15, 2011. View at Publisher · View at Google Scholar · View at Scopus
  7. A. Otani and T. E. Hugli, “Leukocyte chemotaxis: a new in vivo testing technique,” Inflammation, vol. 2, no. 1, pp. 67–82, 1977. View at Publisher · View at Google Scholar · View at Scopus
  8. E. Fujii, K. Irie, A. Ogawa, K. I. Ohba, and T. Muraki, “Role of nitric oxide and prostaglandins in lipopolysaccharide-induced increase in vascular permeability in mouse skin,” European Journal of Pharmacology, vol. 297, no. 3, pp. 257–263, 1996. View at Publisher · View at Google Scholar · View at Scopus
  9. K. Wada, E. Fujii, H. Ishida, T. Yoshioka, and T. Muraki, “Effect of lipoteichoic acid on dermal vascular permeability in mice,” Journal of Pharmacology and Experimental Therapeutics, vol. 294, no. 1, pp. 280–286, 2000. View at Scopus
  10. J. Damas, V. Bourdon, G. Remacle-Volon, and A. Adam, “Kinins and peritoneal exudates induced by carrageenin and zymosan in rats,” British Journal of Pharmacology, vol. 101, no. 2, pp. 418–422, 1990. View at Scopus
  11. R. I. Taber, D. D. Greenhouse, J. K. Rendell, and S. Irwin, “Agonist and antagonist interactions of opioids on acetic acid-induced abdominal stretching in mice,” Journal of Pharmacology and Experimental Therapeutics, vol. 169, no. 1, pp. 29–38, 1969. View at Scopus
  12. M. Shibata, T. Ohkubo, H. Takahashi, and R. Inoki, “Modified formalin test: characteristic biphasic pain response,” Pain, vol. 38, no. 3, pp. 347–352, 1989. View at Scopus
  13. C. A. Winter, E. A. Risley, and G. W. Nuss, “Carrageenin-induced edema in hind paw of the rat as an assay for antiiflammatory drugs,” Proceedings of the Society for Experimental Biology and Medicine, vol. 111, pp. 544–547, 1962. View at Scopus
  14. R. Vinegar, W. Schreiber, and R. Hugo, “Biphasic development of carrageenin edema in rats,” Journal of Pharmacology and Experimental Therapeutics, vol. 166, no. 1, pp. 96–103, 1969. View at Scopus
  15. S. B. Hwang, M. H. Lam, C. L. Li, and T. Y. Shen, “Release of platelet activating factor and its involvement in the first phase of carrageenin-induced rat foot edema,” European Journal of Pharmacology, vol. 120, no. 1, pp. 33–41, 1986. View at Scopus
  16. D. M. Humphrey and C. Cavanaugh, “Microvascular function in skin windows,” American Journal of Pathology, vol. 126, no. 3, pp. 423–431, 1987. View at Scopus
  17. H. Y. Tsai, Y. T. Lin, C. H. Tsai, and Y. F. Chen, “Effects of paeoniflorin on the formalin-induced nociceptive behaviour in mice,” Journal of Ethnopharmacology, vol. 75, no. 2-3, pp. 267–271, 2001. View at Publisher · View at Google Scholar · View at Scopus
  18. L. W. Lin, M. T. Hsieh, F. H. Tsai, W. H. Wang, and C. R. Wu, “Anti-nociceptive and anti-inflammatory activity caused by Cistanche deserticola in rodents,” Journal of Ethnopharmacology, vol. 83, no. 3, pp. 177–182, 2002. View at Publisher · View at Google Scholar · View at Scopus
  19. M. P. Holsapple and G. K. W. Yim, “Therapeutic reduction of ongoing carrageenin-induced inflammation by lipoxygenase, but not cyclooxygenase inhibitors,” Inflammation, vol. 8, no. 3, pp. 223–230, 1984. View at Scopus
  20. D. R. Loyd, M. A. Henry, and K. M. Hargreaves, “Serotonergic neuromodulation of peripheral nociceptors,” Seminars in Cell and Developmental Biology. In press. View at Publisher · View at Google Scholar
  21. J. B. Weinberg, “Nitric oxide as an inflammatory mediator in autoimmune MRL-lpr/lpr mice,” Environmental Health Perspectives, vol. 106, no. 5, pp. 1131–1137, 1998. View at Scopus
  22. N. McCartney-Francis, J. B. Allen, D. E. Mizel et al., “Suppression of arthritis by an inhibitor of nitric oxide synthase,” Journal of Experimental Medicine, vol. 178, no. 2, pp. 749–754, 1993. View at Scopus