Research Article

Ganoderma tsugae Induces S Phase Arrest and Apoptosis in Doxorubicin-Resistant Lung Adenocarcinoma H23/0.3 Cells via Modulation of the PI3K/Akt Signaling Pathway

Figure 1

Quality control of GTE. (a) The 3 GTE samples were derived from the fruiting bodies of an improved strain of Ganoderma tsugae that were collected at three different times. The HPLC chromatogram shows all of the peaks of the components that eluted before 32 minutes. The chemical fingerprints were found to be identical for the 3 batches, and the specific retention time was given in one example. (b) The identical mass fingerprints were also confirmed using ESI-MS. (c) The biological responses for GTE acting on H23/0.3 analyzed by Phytoviewer QC using the whole genomic approach in duplicate experiments (T1, T2) show highly concordant bioresponse fingerprints with a PSI value of 0.98.
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