Ganoderma tsugae Induces S Phase Arrest and Apoptosis in Doxorubicin-Resistant Lung Adenocarcinoma H23/0.3 Cells via Modulation of the PI3K/Akt Signaling Pathway
Figure 7
Effect of GTE on the growth of H23/0.3 xenografted tumors in vivo. (a) The tumor growth rate was significantly retarded in the GTE-treated group (100 mg/kg/day). The tumor volumes were estimated from the caliper measurements of three dimensions of the tumor. The estimated tumor volumes were calculated as , where L is the major axis and W is tumor width. The data are represented as the mean ± SE (). (b) The tumor sections from the control mice showed more mitotic cells compared to those from the GTE-treated mice. The red arrows indicate mitotic figures in the H&E-stained areas (400X).
