Review Article

Systems Biology of Meridians, Acupoints, and Chinese Herbs in Disease

Table 2

List of Chinese herbal studies that have incorporated genomic and proteomic analysis.

Authors Herb name Extracts Common functions

Sliva [65],
Lai et al. [66],
Lin et al. [67],
Cheng et al. [71]
G. lucidum (lingzhi)Polysaccharide fraction/F3 Immunomodulatory,
antitumor activity
Cheng et al. [69] G. sinense (lingzhi)Ethanol extracts Immunomodulatory
Wu et al. [70] C. sappan Protosappanin A Immunomodulatory
Zhang et al. [72] A. Radix and R. Radix NF3 (A. Radix and R. Radix  
in the ratio of 2 : 1)
Wound repair
Zhao et al. [73] A. Sinensis SBD.4 Wound repair
Sun et al. [74] Herba Epimedii,  
Fructus Ligustri Lucidi, and Fructus Psoraleae
Postmenopausal osteoporosis
Han et al. [21] C.A. Meyer CK Diabetes mellitus
Luo et al. [75],
King and Murphy [76]
American ginseng
(P. quinquefolius L.)
Ginsenoside Rg3/ginseng extracts Antitumor activity
Hara et al. [77],
Iizuka et al. [78]
C. rhizome Benzodixoloquinolizine alkaloids/berberine Anti-tumor activity
Wang et al. [79] L. rubescens Oridonin Anti-tumor activity
Xu et al. [80] Franquet TBMS1 Anti-tumor activity
Cheng et al. [81] R. paridis RPTS Anti-tumor activity
Yue et al. [82] P. ginseng Rg1 Angiogenesis
Konkimalla et al. [83] Artemisinin Nitric oxide biosynthesis
Su et al. [20, 84] P. suffruticosa Paeonol Neurodegenerative disease
Wang et al. [85] S. miltiorrhiza SAL or TAN Acute myocardial infarction
Lo et al. [86] U. rhynchophylla Convulsive disorders
Hung et al. [87, 88] S. miltiorrhiza SMAE Cardiovascular disorder