Research Article

Effects of Sangu Decoction on Osteoclast Activity in a Rat Model of Breast Cancer Bone Metastasis

Figure 3

Effects of SGD on the proliferation of TRAP positive polykaryocytes (×1000). (a) Sham-op. group: TRAP positive polykaryocytes were rarely seen. (b) Model group: a large amount of scattered, strongly TRAP positive cells resided in the cancerous bone. (c) Zoledronic acid group and (d) SGD group: bone after treatment with Zoledronic acid or SGD contained only few, faintly stained TRAP positive profiles close to the bone.
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(c)
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