Effects of Sangu Decoction on Osteoclast Activity in a Rat Model of Breast Cancer Bone Metastasis

Table 4

Comparison of TRAP-5b protein levels and TRAP mRNA in different groups (𝑛=6).

Group	TRAP-5b (U/L)		TRAP mRNA (2^−ΔΔCT)
	Serum	Ipsilateral tibia	Ipsilateral tibia
Sham-op.	0.83±0.21^∗∗	0.13±0.01^∗∗	0.98±0.07^∗∗
Model	1.22±0.21^▵▵	0.55±0.06^▵▵	35.43±0.86^▵▵
Zoledronic acid	0.74±0.23^∗∗	0.50±0.15^▵	20.11±0.75^▵▵∗∗
SGD	0.85±0.17^∗∗	0.28±0.10^∗	21.34±1.60^▵▵∗∗

Notes: ▵P < 0.05, ▵▵P < 0.01, compared with the sham-operated group; ∗P < 0.05, ∗∗P < 0.01, compared with the model group.