Review Article

Pomegranate Protection against Cardiovascular Diseases

Figure 7

Pomegranate juice (PJ) reduces oxidative stress in carotid artery stenosis (CAS) patients’ lesion, and in macrophages. Effect of PJ consumption by CAS patients on lipid peroxides content in human carotid lesions (a), and the effect of PJ consumption by E0 mice on lipid peroxides content in their mouse peritoneal macrophages (b). J774A.1 macrophage cell line was incubated with increasing concentrations of PJ for 20 hours at 37°C, followed by cellular oxidative stress analysis measured as DCFH oxidation (c).* (mean SD versus 0 time in humans, and PJ versus placebo in the mice study), # cell incubation with PJ versus control cells (without PJ).
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(a) Carotid Lesion Lipid Peroxides
382763.fig.007b
(b) Macrophage Lipid Peroxides
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(c) Macrophage Total Peroxides