Table 3: Estimation of mean changes in BPI average pain and BPI severity scores*.

Subject numbersBaselineEnd pointMean change
Pain ScoreAnchor statusMean (SD)Mean (SD)Mean (SD)Mean (SD)MCIDs

Worst pain Improved367.47 (1.70)3.32 (2.96)−4.15 (2.37)−1.86 (45.72)
Stable227.76 (1.67)5.47 (3.12)−2.29 (2.42)
Average pain Improved366.03 (1.84)2.25 (2.52)−3.78 (2.18)−0.74 (54.38) 
Stable226.57 (2.04)3.53 (2.53)−3.04 (2.27)
Severity Improved366.09 (1.94)2.27 (2.18)−3.83 (2.05)−1.16 (52.88) 
Stable226.45 (1.86)3.78 (2.59)−2.67 (2.22)
Interference Improved364.82 (2.69)2.02 (2.50)−2.80 (2.60)−0.70 (52.69)
Stable224.65 (2.94)2.55 (2.84)−2.10 (2.90)

MCIDs: minimum clinically important differences.
Grouped according to responses from treatment satisfaction questionnaire.
Expressed as score reduction (Improved, Stable) and percent reduction from baseline.