Absence of Genotoxic and Mutagenic Effects of Zingiber zerumbet (L.) Smith (Zingiberaceae) Extract

Table 2

Results of the chromosomal aberration assay in CHL cells.

Exposure (h)/±S9	Dose (μg mL^−1)	Structural aberrations		Numerical aberrations		Cell growth (%)
		Chromatid break	Chromatid exchange	Polyploidy	Endoreduplication
6/+S9	0	1	0	1	0	100
	150	2	0	1	0	99.2
	300	2	0	1	0	98.3
	600	1	0	0	0	99.4
	1250	2	0	1	0	98.5
	2500	1	0	0	0	99.1
	5000	3	1	1	0	97.8
	B[a]P 0.2	25	37	6	2	61.3
6/−S9	0	1	0	0	0	100
	150	3	0	2	0	99.3
	300	3	0	1	0	98.2
	600	2	0	1	0	97.6
	1250	2	0	1	0	98.1
	2500	3	0	0	0	97.4
	5000	3	1	0	0	96.5
	B[a]P 0.15	25	36	5	2	57.2
24/−S9	0	0	0	1	0	100
	150	4	0	1	0	99.3
	300	3	0	2	0	97.9
	600	1	0	0	0	98.2
	1250	2	0	1	0	96.8
	2500	1	0	0	0	97.4
	5000	3	0	2	0	98.6
	MMC 0.05	36	44	3	1	62.3
48/−S9	0	0	0	1		100
	150	0	0	0	0	99.6
	300	1	0	1	0	98.2
	600	3	0	1	0	98.1
	1250	3	0	0	0	97.9
	2500	1	0	0	0	98.2
	5000	1	0	1	0	97.6
	MMC 0.05	26	0	4	1	60.4