Polyphenol-Rich Fraction of Brown Alga Ecklonia cava Collected from Gijang, Korea, Reduces Obesity and Glucose Levels in High-Fat Diet-Induced Obese Mice

Figure 2

Effect of CA or G-CA extracts on total fat mass and fat tissue weight. Three weeks after beginning a high-fat diet, C57BL6 mice were orally administered CA or G-CA extract (200 mg/kg body weight) or PBS daily. (a) After 8 weeks of CA and G-CA treatment, total fat mass was measured by mini-spec. After 8 weeks of CA and G-CA treatment, ((b)–(e)) fat pads and (f) liver tissue were collected and weighed. Values are the average tissue weight as a proportion of body weight. NC: untreated, normal chow diet; PBS: PBS-treated, high-fat diet (HFD); CA: CA-treated, HFD; G-CA: G-CA-treated, HFD; 𝑛=5/group. Values are mean ± SE. ^∗∗𝑃<0.01 versus NC group; ^##𝑃<0.01 versus PBS-HFD group; ^$𝑃<0.05, ^$$𝑃<0.01 versus CA-HFD.

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