Polyphenol-Rich Fraction of Brown Alga Ecklonia cava Collected from Gijang, Korea, Reduces Obesity and Glucose Levels in High-Fat Diet-Induced Obese Mice

Figure 3

Effect of CA or G-CA extracts on blood glucose levels and glucose tolerance. Three weeks after beginning a high-fat diet, C57BL6 mice were orally administered CA or G-CA extract (200 mg/kg body weight) or PBS daily. At 7 weeks of treatment, (a) blood glucose levels were measured in mice fasted overnight (𝑛 = 6–8) and (b) intraperitoneal glucose tolerance tests were performed (200 mg/kg glucose body weight, 𝑛=5). Values are mean ± SE. NC: untreated, normal chow diet; PBS: PBS-treated, high-fat diet (HFD); CA: CA-treated, HFD; G-CA: G-CA-treated, HFD. Values are mean ± SE. ^∗𝑃<0.05, ^∗∗𝑃<0.01 versus NC group; ^#𝑃<0.05, ^##𝑃<0.01 versus PBS-HFD group; ^$𝑃<0.05, ^$$𝑃<0.01 versus CA-HFD.

(a)

(b)