Phytochemical Analysis and Antimicrobial, Antinociceptive, and Anti-Inflammatory Activities of Two Chemotypes of Pimenta pseudocaryophyllus (Myrtaceae)

Figure 3

Antinociceptive effect of fractions in the abdominal contortion model induced by acetic acid (1.2% v/v, i.p.) in mice previously treated with HF_C (400 mg kg⁻¹, v.o), DF_C (240 mg kg⁻¹, v.o), EAF_C (1160 mg kg⁻¹, v.o), and AF_C (480 mg kg⁻¹, v.o). Vehicle (water + DMSO 10%) 10 mL kg⁻¹, v.o. Each column shows the mean (±SEM) of number of contortions in percentages relative to control (vehicle). *Indicates the significance level compared to the control group (vehicle). 𝑛=10 mice. *𝑃<0.05, **𝑃<0.01, ***𝑃<0.001.