About this Journal Submit a Manuscript Table of Contents
Evidence-Based Complementary and Alternative Medicine
Volume 2012 (2012), Article ID 426537, 13 pages
http://dx.doi.org/10.1155/2012/426537
Research Article

Syringic Acid Extracted from Herba dendrobii Prevents Diabetic Cataract Pathogenesis by Inhibiting Aldose Reductase Activity

1School of Basic Medical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, China
2School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510275, China

Received 6 September 2012; Revised 25 November 2012; Accepted 2 December 2012

Academic Editor: Bhushan Patwardhan

Copyright © 2012 Xiaoyong Wei et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. A. Pollreisz and U. Schmidt-Erfurth, “Diabetic cataract-pathogenesis, epidemiology and treatment,” Journal of Ophthalmology, vol. 2010, Article ID 608751, 5 pages, 2010. View at Publisher · View at Google Scholar
  2. A. B. M. Reddy, R. Tammali, R. Mishra, S. Srivastava, S. K. Srivastava, and K. V. Ramana, “Aldose reductase deficiency protects sugar-induced lens opacification in rats,” Chemico-Biological Interactions, vol. 191, no. 1–3, pp. 346–350, 2011. View at Publisher · View at Google Scholar · View at Scopus
  3. P. Anil Kumar and G. Bhanuprakash Reddy, “Focus on Molecules: aldose reductase,” Experimental Eye Research, vol. 85, no. 6, pp. 739–740, 2007. View at Publisher · View at Google Scholar · View at Scopus
  4. K. Kawakubo, A. Mori, K. Sakamoto, T. Nakahara, and K. Ishii, “GP-1447, an inhibitor of aldose reductase, prevents the progression of diabetic cataract in rats,” Biological and Pharmaceutical Bulletin, vol. 35, no. 6, pp. 866–872, 2012.
  5. J. Kim, C.-S. Kim, E. Sohn, Y. M. Lee, and J. S. Kim, “KIOM-79 inhibits aldose reductase activity and cataractogenesis in Zucker diabetic fatty rats,” Journal of Pharmacy and Pharmacology, vol. 63, no. 10, pp. 1301–1308, 2011. View at Publisher · View at Google Scholar
  6. N. Hotta, Y. Akanuma, R. Kawamori et al., “Long-term clinical effects of epalrestat, an aldose reductase inhibitor, on diabetic peripheral neuropathy: the 3-year, multicenter, comparative aldose reductase inhibitor-diabetes complications trial,” Diabetes Care, vol. 29, no. 7, pp. 1538–1544, 2006. View at Publisher · View at Google Scholar · View at Scopus
  7. S. Misawa, S. Kuwabara, K. Kanai et al., “Aldose reductase inhibition alters nodal Na+ currents and nerve conduction in human diabetics,” Neurology, vol. 66, no. 10, pp. 1545–1549, 2006. View at Publisher · View at Google Scholar · View at Scopus
  8. D. K. Patel, R. Kumar, D. Laloo, and S. Hemalatha, “Evaluation of phytochemical and antioxidant activities of the different fractions of Hybanthus enneaspermus (Linn.) F. Muell. (Violaceae),” Asian Pacific Journal of Tropical Medicine, vol. 4, no. 5, pp. 391–396, 2011. View at Publisher · View at Google Scholar · View at Scopus
  9. R. N. Gacche and N. A. Dhole, “Aldose reductase inhibitory, anti-cataract and antioxidant potential of selected medicinal plants from the Marathwada region, India,” Natural Product Research, vol. 25, no. 7, pp. 760–763, 2011. View at Publisher · View at Google Scholar · View at Scopus
  10. J. Lee, D. S. Jang, N. H. Kim, Y. M. Lee, J. Kim, and J. S. Kim, “Galloyl glucoses from the seeds of Cornus officinalis with inhibitory activity against protein glycation, aldose reductase, and cataractogenesis ex vivo,” Biological and Pharmaceutical Bulletin, vol. 34, no. 3, pp. 443–446, 2011. View at Publisher · View at Google Scholar · View at Scopus
  11. Commission of Chinese Pharmacopoeia, Pharmacopoeia of the People’s Republic of China, China Medical Science and Technology Press, Beijing, China, pp. 264–265, 2010.
  12. J. I. Song, Y. J. Kang, H.-Y. Yong, Y. C. Kim, and A. Moon, “Denbinobin, a phenanthrene from Dendrobium nobile, inhibits invasion and induces apoptosis in SNU-484 human gastric cancer cells,” Oncology Reports, vol. 27, no. 3, pp. 813–818, 2012. View at Publisher · View at Google Scholar
  13. M. Y. Yoon, J. H. Hwang, J. H. Park et al., “Neuroprotective effects of SG-168 against oxidative stress-induced apoptosis in PC12 cells,” Journal of Medicinal Food, vol. 14, no. 1-2, pp. 120–127, 2011. View at Publisher · View at Google Scholar · View at Scopus
  14. Y. Li, F. Li, Q. Gong, Q. Wu, and J. Shi, “Inhibitory effects of dendrobium alkaloids on memory impairment induced by lipopolysaccharide in rats,” Planta Medica, vol. 77, no. 2, pp. 117–121, 2011. View at Publisher · View at Google Scholar · View at Scopus
  15. J. S. Hwang, S. A. Lee, S. S. Hong et al., “Phenanthrenes from Dendrobium nobile and their inhibition of the LPS-induced production of nitric oxide in macrophage RAW 264.7 cells,” Bioorganic and Medicinal Chemistry Letters, vol. 20, no. 12, pp. 3785–3787, 2010. View at Publisher · View at Google Scholar · View at Scopus
  16. A. Luo, X. He, S. Zhou, Y. Fan, T. He, and Z. Chun, “In vitro antioxidant activities of a water-soluble polysaccharide derived from Dendrobium nobile Lindl. extracts,” International Journal of Biological Macromolecules, vol. 45, no. 4, pp. 359–363, 2009. View at Publisher · View at Google Scholar · View at Scopus
  17. “Studies on antioxidant activity of benzyl and phenolic components from Dendrobium nobil,” J Chin Pham, vol. 43, no. 11, pp. 839–842, 2008.
  18. A. Meissner and T. Noack, “Proliferation of human lens epithelial cells (HLE-B3) is inhibited by blocking of voltage-gated calcium channels,” Pflugers Archiv European Journal of Physiology, vol. 457, no. 1, pp. 47–59, 2008. View at Publisher · View at Google Scholar · View at Scopus
  19. M. Azuma, T. R. Shearer, T. Matsumoto, L. L. David, and T. Murachi, “Calpain II in two in vivo models of sugar cataract,” Experimental Eye Research, vol. 51, no. 4, pp. 393–401, 1990. View at Publisher · View at Google Scholar · View at Scopus
  20. Ganeshpurkar, S. S. Bhadoriya, P. Pardhi, A. P. Jain, and G. Rai, “In vitro prevention of cataract by Oyster Mushroom Pleurotus florida extract on isolated goat eye lens,” Indian Journal of Pharmacology, vol. 43, pp. 667–670, 2011.
  21. M. M. Bradford, “A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding,” Analytical Biochemistry, vol. 72, no. 1-2, pp. 248–254, 1976. View at Scopus
  22. P. K. Sahoo and P. Behera, “Synthesis and biological evaluation of [1,2,4]triazino[4,3-a] benzimidazole acetic acid derivatives as selective aldose reductase inhibitors,” European Journal of Medicinal Chemistry, vol. 45, no. 3, pp. 909–914, 2010. View at Publisher · View at Google Scholar · View at Scopus
  23. N. Halder, S. Joshi, and S. K. Gupta, “Lens aldose reductase inhibiting potential of some indigenous plants,” Journal of Ethnopharmacology, vol. 86, no. 1, pp. 113–116, 2003. View at Publisher · View at Google Scholar · View at Scopus
  24. Z. Wang, B. Ling, R. Zhang et al., “Docking and molecular dynamics studies toward the binding of new natural phenolic marine inhibitors and aldose reductase,” Journal of Molecular Graphics and Modelling, vol. 28, no. 2, pp. 162–169, 2009. View at Publisher · View at Google Scholar · View at Scopus
  25. C. Koukoulitsa, F. Bailly, K. Pegklidou, V. J. Demopoulos, and P. Cotelle, “Evaluation of aldose reductase inhibition and docking studies of 6′-nitro and 6′,6′-dinitrorosmarinic acids,” European Journal of Medicinal Chemistry, vol. 45, no. 4, pp. 1663–1666, 2010. View at Publisher · View at Google Scholar · View at Scopus
  26. H. Steuber, M. Zentgraf, C. Gerlach, C. A. Sotriffer, A. Heine, and G. Klebe, “Expect the unexpected or caveat for drug designers: multiple structure determinations using aldose reductase crystals treated under varying soaking and co-crystallisation conditions,” Journal of Molecular Biology, vol. 363, no. 1, pp. 174–187, 2006. View at Publisher · View at Google Scholar · View at Scopus
  27. R. Maccari, R. Ciurleo, M. Giglio et al., “Identification of new non-carboxylic acid containing inhibitors of aldose reductase,” Bioorganic and Medicinal Chemistry, vol. 18, no. 11, pp. 4049–4055, 2010. View at Publisher · View at Google Scholar · View at Scopus
  28. R. Maccari, R. Ottanà, R. Ciurleo et al., “Synthesis, induced-fit docking investigations, and in vitro aldose reductase inhibitory activity of non-carboxylic acid containing 2,4-thiazolidinedione derivatives,” Bioorganic and Medicinal Chemistry, vol. 16, no. 11, pp. 5840–5852, 2008. View at Publisher · View at Google Scholar · View at Scopus
  29. J. Y. Xu, L. Y. Wu, X. Q. Zheng, J. L. Lu, M. Y. Wu, and Y. R. Liang, “Green tea polyphenols attenuating ultraviolet B-induced damage to human retinal pigment epithelial cells in vitro,” Investigative Ophthalmology and Visual Science, vol. 51, no. 12, pp. 6665–6670, 2010. View at Publisher · View at Google Scholar · View at Scopus
  30. C. Day, “The rising tide of type 2 diabetes,” The British Journal of Diabetes & Vascular Disease, vol. 1, no. 1, pp. 37–43, 2001.
  31. Z. Kyselova, M. Stefek, and V. Bauer, “Pharmacological prevention of diabetic cataract,” Journal of Diabetes and its Complications, vol. 18, no. 2, pp. 129–140, 2004. View at Publisher · View at Google Scholar · View at Scopus
  32. Z. Hashim and S. Zarina, “Osmotic stress induced oxidative damage: possible mechanism of cataract formation in diabetes,” Journal of Diabetes and Its Complications, vol. 26, no. 4, pp. 275–279, 2012.
  33. M. L. Mulhern, C. J. Madson, A. Danford, K. Ikesugi, P. F. Kador, and T. Shinohara, “The unfolded protein response in lens epithelial cells from galactosemic rat lenses,” Investigative Ophthalmology and Visual Science, vol. 47, no. 9, pp. 3951–3959, 2006. View at Publisher · View at Google Scholar · View at Scopus
  34. D. C. Kosegarten and T. J. Maher, “Use of guinea pigs as model to study galactose-induced cataract formation,” Journal of Pharmaceutical Sciences, vol. 67, no. 10, pp. 1478–1479, 1978. View at Scopus
  35. P. Suryanarayana, K. Krishnaswamy, and G. Bhanuprakash Reddy, “Effect of curcumin on galactose-induced cataractogenesis in rats,” Molecular Vision, vol. 9, pp. 223–230, 2003. View at Scopus
  36. Y. S. Kim, N. H. Kim, Y. M. Lee, and J. S. Kim, “Preventive effect of chlorogenic acid on lens opacity and cytotoxicity in human lens epithelial cells,” Biological and Pharmaceutical Bulletin, vol. 34, no. 6, pp. 925–928, 2011. View at Publisher · View at Google Scholar · View at Scopus