Herb-Drug Interaction of <i>Paullinia cupana</i> (Guarana) Seed Extract on the Pharmacokinetics of Amiodarone in Rats

<table>Chemical structures of amiodarone and its major metabolite mono-<i>N</i>-desethylamiodarone (MDEA).</table>

Evidence-Based Complementary and Alternative Medicine

Figure 1: Herb-Drug Interaction of <i>Paullinia cupana</i> (Guarana) Seed Extract on the Pharmacokinetics of Amiodarone in Rats 