Anti-Inflammatory Activities of Cinnamomum cassia Constituents In Vitro and In Vivo

Table 1

Effects of cinnamic aldehyde and indomethacin (Indo) on changes in CAT, SOD, and GPx activities were studied in Carr-induced paw edema (5th h) in mice.

Groups	Catalase	SOD	GPx
	(U/mg protein)	(U/mg protein)	(U/mg protein)
Control	5.89 ± 0.12	21.58 ± 0.08	28.26 ± 0.21
Carr	3.68 ± 0.04^###	12.46 ± 0.13^###	16.68 ± 0.19^###
Carr + Indo	5.27 ± 0.16**	20.06 ± 0.19**	26.32 ± 0.19***
Carr + cinnamic aldehyde (1.25 mg/Kg)	3.89 ± 0.13	14.59 ± 0.15	17.59 ± 0.16
Carr + cinnamic aldehyde (2.5 mg/Kg)	4.59 ± 0.19*	16.61 ± 0.21*	21.27 ± 0.25*
Carr + cinnamic aldehyde (5 mg/Kg)	5. 21 ± 0.19**	20.83 ± 0.17**	25.26 ± 0.24**

Each value represents as mean ± S.E.M. ^###𝑃<0.001 as compared with control group. ^∗𝑃<0.05, ^∗∗𝑃, and ^∗∗∗𝑃<0.001 as compared with the Carr (𝜆-carrageenan) group (one-way ANOVA followed by Scheffe’s multiple range test).