In Vitro Assessment of Cytochrome P450 2C19 Potential of Naoxintong

<table class="table-group" id="tab2"><tr><td><table class="table"><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr class="thead"><td align="left">Joined concentration</td><td align="center" rowspan="2">Extraction recovery (%)</td><td align="center" rowspan="2">RSD (%)</td></tr><tr class="thead"><td align="left">(ng/mL)</td></tr><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr><td align="left">230</td><td align="center"><span style="width: 66.199997px;"><svg height="11.2875" id="M11" style="vertical-align:-0.3003pt" version="1.1" viewbox="0 0 66.199997 11.2875" width="66.199997" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg></span></td><td align="center">4.4%</td></tr><tr><td align="left">2300</td><td align="center"><span style="width: 66.199997px;"><svg height="11.4" id="M12" style="vertical-align:-0.3003pt" version="1.1" viewbox="0 0 66.199997 11.4" width="66.199997" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,0,0,-.017,.062,10.963)"><path d="M244 635q90 0 143 -72t53 -177q0 -133 -65 -229.5t-171 -139.5q-79 -32 -140 -32l-5 30q109 18 185 91t101 186l-68 -36q-29 -16 -60 -16q-79 0 -129 51.5t-50 130.5q0 80 57 146.5t149 66.5zM228 602q-52 0 -78 -45.5t-26 -98.5q0 -69 36.5 -115.5t97.5 -46.5
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q0 45 -26.5 69.5t-68.5 24.5q-67 0 -120 -79l-20 20l43 63q51 56 127 56h1q66 0 107 -37t41 -95q0 -42 -31 -71q-22 -23 -68 -54z" id="x33"></path></g><g transform="matrix(.017,0,0,-.017,54.102,10.963)"><path d="M113 -12q-24 0 -39.5 16t-15.5 42q0 24 16 40.5t40 16.5t40 -16.5t16 -40.5q0 -26 -16 -42t-41 -16z" id="x2E"></path></g><g transform="matrix(.017,0,0,-.017,57.977,10.963)"><path d="M244 635q90 0 143 -72t53 -177q0 -133 -65 -229.5t-171 -139.5q-79 -32 -140 -32l-5 30q109 18 185 91t101 186l-68 -36q-29 -16 -60 -16q-79 0 -129 51.5t-50 130.5q0 80 57 146.5t149 66.5zM228 602q-52 0 -78 -45.5t-26 -98.5q0 -69 36.5 -115.5t97.5 -46.5
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</svg></span></td><td align="center">4.0%</td></tr><tr><td align="left">5800</td><td align="center"><span style="width: 82.525002px;"><svg height="11.2875" id="M13" style="vertical-align:-0.3003pt" version="1.1" viewbox="0 0 82.525002 11.2875" width="82.525002" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg></span></td><td align="center">2.6%</td></tr><tr class="table-tr"><td colspan="3"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

The extraction recovery of 4′-OH-mephenytoin (mean ± SD, <svg height="10.925" id="M10" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 36.237499 10.925" width="36.237499" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>).

Evidence-Based Complementary and Alternative Medicine

In Vitro Assessment of Cytochrome P450 2C19 Potential of Naoxintong

Table 2