Table 3: Comparison of the amount of 4′-OH-mephenytoin among blank group, positive control group, and trial group.

Blank group ( )Positive control group (phenytoin sodium, ) Trial group (BNC, )

Incubation final concentration (μg/mL)0.3550100150200250
4′-OH-M (nmol/mg·h)
▲▲▲▲▲,△△,▲▲,△△△,♀♀,▲▲▲,△△△,♀♀♀,††

Note: values are presented as mean ± SD.
▲▲▲, △△△, ♀♀♀: compared with blank, 5 μg/mL, 50 μg/mL, 100 μg/mL, respectively, .
▲▲, △△, ♀♀, ††: compared with blank, 5 μg/mL, 50 μg/mL, 100 μg/mL, respectively, .
♀, †: compared with 5 μg/mL, 50 μg/mL, respectively, .