Efficacy and Safety of a Chinese Herbal Medicine Formula (RCM-104) in the Management of Simple Obesity: A Randomized, Placebo-Controlled Clinical Trial
Table 3
Obesity and weight-loss quality of life-your feelings about your weight.
Symptoms
Study period
RCM-104 ()# value ± SD
Placebo () value ± SD
value**
Because of my weight, I try to wear clothes that hide my shape
Baseline
Final
value*
<0.001
0.033
0.021
I feel frustrated that I have less energy because of my weight
Baseline
Final
value*
<0.001
0.058
0.025
I feel guilty when I eat because of my weight
Baseline
Final
value*
<0.001
0.025
0.093
I am bothered about what other people say about my weight
Baseline
Final
value*
0.033
0.047
0.590
Because of my weight, I try to avoid having my photograph taken
Baseline
Final
value*
0.002
0.016
0.374
My weight prevents me from doing what I want to do
Baseline
Final
value*
0.045
0.001
0.608
I worry about the physical stress that my weight puts on my body
Baseline
Final
value*
0.003
0.028
0.329
I feel depressed because of my weight
Baseline
Final
value*
0.001
0.148
0.106
I feel ugly because of my weight
Baseline
Final
value*
<0.001
0.002
0.072
I worry about the future because of my weight
Baseline
Final
value*
<0.001
0.231
0.702
I envy people who are thin
Baseline
Final
value*
<0.001
0.382
0.267
I feel that people stare at me because of my weight
Baseline
Final
value*
0.014
0.254
0.332
I have difficulty accepting my body because of my weight
Baseline
Final
value*
0.006
0.170
0.179
I am afraid that I will gain back any weight that I lose
Baseline
Final
value*
0.002
0.019
0.149
I get discouraged when I try to lose weight
Baseline
Final
value*
<0.001
0.848
0.002
Obesity & Weight-Loss Quality of Life measure (OWLQOL) questionnaires are 7-point scaled: 0 = not at all; 1 = hardly; 2 = somewhat; 3 = moderately; 4 = a good deal; 5 = a great deal; 6 = a very great deal.
*Comparison within the group between baseline and final visits using Wilcoxon signed-rank test.
**Comparison between groups at the end of trial. For both the above, the values were assessed using Holm’s step-down procedure, with for assessing the smallest value, α = 0.05/16 = 0.0031 for the next smallest value, and so forth. Significant values are indicated in bold. Note: only symptoms showing small values are displayed. #Sample size for treatment group reduced from 50 to 48 as Quality of Life data were unavailable for two participants.