Evidence-Based Complementary and Alternative Medicine / 2012 / Article / Tab 4 / Review Article
Role of Mesotherapy in Musculoskeletal Pain: Opinions from the Italian Society of Mesotherapy Table 4 Randomized, controlled clinical trial in patients with low back pain, cervicobrachialgia and calcific painful tendinitis of the shoulder.
Study Disease No. of patients Study characteristics Drugs utilized Control Period of followup No. of sessions Outcome Parrini et al. 2002 [53 ] Acute lumbosciatic pain syndrome 44 RA Acetylsalicylic acid PC 1 day 1 Pain reduction/safety Monticone et al. 2004 [54 ] Low back pain (sacroiliac dysfunction) 22 RA P C NSAIDs Laser therapy 1 year 2 session per week (8 sessions) Pain reduction better for mesotherapy, exercise and dynamic support than laser therapy Costantino et al. 2010 [55 ] Low back pain 84 RA P C Lidocaine, ketoprofen, and methylprednisolone Standard therapy ketoprofen, esomeprazole and methylprednisolone 6 months 5 sessions Same efficacy and safety systemic therapy Di Cesare et al. 2010 [56 ] Low back pain 62 RA P C Lidocaine Mesotherapy in acupuncture points versus mesotherapy in trigger points 12 weeks 4 sessions Better reduction of pain with mesotherapy in acopunture points Cacchio et al. 2009 [57 ] Calcific tendinitis of the shoulder 80 RA DB Disodium EDTA and procaine PC 1 year 1 session at weekly intervals for 3 weeks Calcification disappeared completely in 62.5% and partially in 22.5% of pts; partially effects were registered in 15% of pts in the control group Palermo et al. 1991 [60 ] Cervicobrachialgia 20 RA P O C Lidocaine and myorelaxant TENS 20 days 6 TENS 4 mesotherapy Mesotherapy combined with TENS improves symptoms management, and reduces the number of needed TENS sessions
The table lists clinical studies or case reports to evaluate the reduction of pain in various clinical conditions. The pain was noted with visual scales. P: prospective, O: open, DB: double blind, RA: randomized, C: controlled, and PC: placebo controlled.