NMDA Receptor-Dependent Synaptic Activity in Dorsal Motor Nucleus of Vagus Mediates the Enhancement of Gastric Motility by Stimulating ST36

Figure 4

Low frequency stimulation at ST36 decreases paired-pulse ratio (PPR) of NMDAR-mediated EPSC. (a), (b) Representative traces of NMDAR- or AMPAR-mediated EPSC induced by paired-pulse stimulation in NTS. (c) ST36 stimulation decreases PPR of NMDAR-mediated EPSC in labeled DMV neurons. ^∗∗𝑃<0.01, compared to the unlabeled neurons from the stimulated group; ^##𝑃<0.01, compared to the labeled neurons from control; 𝑛=10, unpaired 𝑡 test. (d) ST36 stimulation fails to cause significant change of PPR of AMPAR-mediated EPSC in labeled and unlabeled neurons in both groups, unpaired 𝑡 test.

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