Mixture of Polyphenols and Anthocyanins from Vaccinium uliginosum L. Alleviates DNCB-Induced Atopic Dermatitis in NC/Nga Mice
Figure 4
Histological changes by the mixture treatment. H&E or toluidine blue stained sections were observed under microscope at a magnification of 400. (a) H&E stained lesional skin of normal, AD(negative control), prednisolone(positive control), poly+antho 2.56 + 7.31, 5.12 + 14.62, and 10.25 + 29.25 mg/mL treated groups (a) epidermal thickness and (b) infiltration of eosinophil was quantified as means in randomly selected four fields per mouse (d) Toluidine blue stained lesional skin of normal, AD(negative control), prednisolone(positive control), poly+antho 2.56 + 7.31, 5.12 + 14.62, and 10.25 + 29.25 mg/mL treated groups (e) infiltration of mast cell and (f) infiltration of degranulatd mast cell were quantified as means in randomly selected four fields per mouse. Scale bar = 100 μm. Data are expressed as means ± SD of 5 mice per group. ###P 0.001, significantly different from the normal group. ***P 0.001, significantly different from the AD group.
