Impact of Global Normalization in fMRI Acupuncture Studies

Table 4

Changes of deactivations between PSGS and NO PSGS.

Regions			Tactile				Acupuncture
		Increased voxels no.	Decreased voxels no.	Disappeared voxels no.	Arisen voxels no.	Increased voxels no.	Decreased voxels no.	Disappeared voxels no.	Arisen voxels no.
Brainstem
Pons	L								2
Medulla	R								3
Medial frontal gyrus
BA 6, 8, 9, 10	L				14 (44)				5 (24)
	R	6 (11)	5 (5)		37 (82)				(9)
Middle frontal gyrus
BA 6, 8, 9	L				10 (27)				16 (13)
	R	18 (5)			59 (77)	5			38 (37)
Superior frontal gyrus
BA 6, 8	L				12 (66)				34 (37)
	R				36 (43)	6			37 (28)
Paracentral lobule
BA 4, 6	L				6
	R				13 (23)
Precentral gyrus
BA 4, 6, 43, 44	L	19 (66)	(7)		55 (134)				(31)
	R	62 (98)			86 (133)				19 (34)
Anterior cingulate
BA24, 33	L				7 (38)			(5)	(15)
	R				(5)
Cingulate gyrus
BA 24, 32	L				(14)
	R				15 (39)
Cingulate gyrus
BA 31	L								18 (10)
	R								13 (32)
Postcentral gyrus
BA 1, 2, 3	L				28 (35)
	R	26 (13)	17 (13)		29 (38)				31
BA 40, 43	L
	R								(16)
BA 5, 7	R				9
Inferior parietal lobule
BA 39	R				(12)				7 (12)
Superior parietal lobule
BA 7	L	15 (7)			22 (12)				8 (8)
	R	63 (29)			34 (13)				33 (27)
Supramarginal gyrus
BA 40	L								(6)
	R								(13)
Thalamus	R				5				8
Caudate	L				10
Extranuclear
BA 13	L	(40)	(5)	(7)	(94)		(13)	(10)	(45)
	R	(28)	(22)	(8)	(139)		(53)	(7)	(96)
Subgyral
BA 21	L	(169)	(51)	(23)	(494)		(41)	(30)	(150)
	R	7 (200)	(105)	(71)	15 (687)		(146)	(79)	(532)
Posterior cingulate
BA 30, 31	L				13 (30)				7 (41)
	R				(32)				15 (70)
Precuneus
BA 7, 19, 31, 39	L	93 (73)			139 (221)				158 (203)
	R	88 (89)			148 (220)				160 (214)
Parahippocampal gyrus
BA 19, 30, 35, 36	L				32 (69)				8 (69)
	R				8 (30)	7			52 (89)
Hippocampus	L				5				6
	R					5			11
Inferior temporal gyrus
BA 20, 21	L								5 (16)
	R								5 (9)
Middle temporal gyrus
BA 37, 39	L				13 (33)				5 (6)
	R	(18)			8 (114)				42 (88)
Superior temporal gyrus
BA 22, 38, 41, 42	R								(8)
Angular gyrus
BA 39	L								5 (28)
	R	(5)			5 (12)				10 (33)
Fusiform gyrus
BA 20, 37	L				9 (8)				5 (7)
	R				7				20 (23)
Cuneus
BA 17, 18, 19, 7	L	28			110 (190)				52 (98)
	R	37			112 (127)				93 (158)
Inferior occipital gyrus
BA 19	R								6 (17)
Middle occipital gyrus
BA 18, 19, 37	L	(6)			27 (152)				29 (42)
	R	(28)		(6)	27 (126)				82 (202)
Superior occipital gyrus
BA 19	L	12 (8)			12 (8)
	R				14 (13)				6 (9)
Lingual gyrus
BA 17, 18, 19	L				11 (15)				(8)
	R				6 (13)				12 (22)
Cerebellum
Culmen	L				110				11
	R				18

The coordination of voxel with the maximal t within each region is listed. The regions are thresholded at 𝑃<0.001, uncorrected. The number of detected white matter is listed in the parenthesis of each region
Abbreviations: BA: Brodmann area; L: left; R: right.