Red Ginseng Extract Attenuates Kainate-Induced Excitotoxicity by Antioxidative Effects
Figure 4
Effect of RGE and scavengers on MDA levels in KA-treated hippocampal tissue homogenates. Male mice were grouped ( or 6/group) and pretreated (i.p. injection) with RGE (30–200 mg/kg) and scavengers such as trolox (50 mg/kg, i.p.) and DMTU (50 mg/kg, i.p.), or NaCl (0.9%). Thirty minutes after the final RGE or saline pretreatment, seizures in the KA, scavengers + KA, and RGE + KA groups were induced by KA injection (30 mg/kg, i.p.); the mice in the saline group received an equal volume of 0.9% NaCl. All data are presented as means ± SE. ### versus the control group. **, *** versus the KA group.
