Red Ginseng Extract Attenuates Kainate-Induced Excitotoxicity by Antioxidative Effects
Figure 6
Reduction activity of RGE on •OH. (a) ESR spectra of the DMPO/•OH adduct were generated in a Fenton Reaction System. The solutions with a final volume of 0.1 mL contained 2.0 mM ferrous sulfate, 2.0 mM H2O2, and 100 mM phosphate buffer (pH 7.2). Reactions were started by the addition of ferrous ammonium sulfate (2.0 mM final concentration), and the steady-state ESR spectra were recorded at 15 min after the Fenton Reaction. Upper line, DMPO/•OH adduct; lower line, RGE (1.0 mg/mL). (b) Time course of •OH degradation induced by the Fenton Reaction System. DMPO/•OH adduct, RGE (1.0 mg/mL), trolox (1.0 mM), and DMTU (1 mM).
