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Evidence-Based Complementary and Alternative Medicine
Volume 2012 (2012), Article ID 485262, 10 pages
Dual Roles of Quercetin in Platelets: Phosphoinositide-3-Kinase and MAP Kinases Inhibition, and cAMP-Dependent Vasodilator-Stimulated Phosphoprotein Stimulation
1Laboratory of Physiology & Cell Signaling, College of Veterinary Medicine, Kyungpook National University, Daegu 702-701, Republic of Korea
2Department of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, Kyungpook National University, Daegu 702-701, Republic of Korea
3Department of Genetic Engineering, Sungkyunkwan University, Suwon 440-746, Republic of Korea
Received 25 August 2012; Revised 29 October 2012; Accepted 30 October 2012
Academic Editor: Kashmira Nanji
Copyright © 2012 Won Jun Oh et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Citations to this Article [11 citations]
The following is the list of published articles that have cited the current article.
- Eduardo Fuentes, and Iván Palomo, “Antiplatelet effects of natural bioactive compounds by multiple targets: Food and drug interactions,” Journal of Functional Foods, 2013.
- Eduardo Fuentes, and Iván Palomo, “Relationship between Platelet PPARs, cAMP Levels, and P-Selectin Expression: Antiplatelet Activity of Natural Products,” Evidence-Based Complementary and Alternative Medicine, vol. 2013, pp. 1–10, 2013.
- Qian Yang, Weidong Cao, Xuanxuan Zhou, Wei Cao, Yanhua Xie, and Siwang Wang, “Anti-thrombotic effects of alpha-linolenic acid isolated from Zanthoxylum bungeanum Maxim seeds,” Bmc Complementary and Alternative Medicine, vol. 14, 2014.
- Xiaohong Wang, Heinz C. Schröder, Qingling Feng, Bärbel Diehl-Seifert, Vladislav A. Grebenjuk, and Werner E.G. Müller, “Isoquercitrin and polyphosphate co-enhance mineralization of human osteoblast-like SaOS-2 cells via separate activation of two RUNX2 cofactors AFT6 and Ets1,” Biochemical Pharmacology, 2014.
- Dong-Seon Kim, Hyun Dong Ji, Man Hee Rhee, Yoon-Young Sung, Won-Kyung Yang, Seung Hyung Kim, and Ho-Kyoung Kim, “Antiplatelet Activity of Morus alba Leaves Extract, Mediated via Inhibiting Granule Secretion and Blocking the Phosphorylation of Extracellular-Signal-Regulated Kinase and Akt,” Evidence-Based Complementary and Alternative Medicine, vol. 2014, pp. 1–11, 2014.
- Bo Ra Jeon, Su Jung Kim, Seung Bok Hong, Hwa-Jin Park, Jae Youl Cho, and Man Hee Rhee, “The inhibitory mechanism of crude saponin fraction from Korean Red Ginseng in collagen-induced platelet aggregation,” Journal of Ginseng Research, 2015.
- Jung-Hae Shin, Hyuk-Woo Kwon, Hyun-Jeong Cho, Man Hee Rhee, and Hwa-Jin Park, “Vasodilator-stimulated phosphoprotein-phosphorylation by ginsenoside Ro inhibits fibrinogen binding to αIIb/β3 in thrombin-induced human platelets,” Journal of Ginseng Research, 2015.
- Christine N. Galinski, Jeffrey I. Zwicker, and Daniel R. Kennedy, “Revisiting the mechanistic basis of the French Paradox: Red wine inhibits the activity of protein disulfide isomerase in vitro,” Thrombosis Research, 2015.
- Hong-Zhen Hao, Ao-Di He, Dao-Chun Wang, Zhao Yin, Ya-Jun Zhou, Gang Liu, Ming-Lu Liang, Xing-Wen Da, Guang-Qiang Yao, Wen Xie, Ji-Zhou Xiang, and Zhang-Yin Ming, “Antiplatelet activity of loureirin A by attenuating Akt phosphorylation: In vitro studies,” European Journal Of Pharmacology, vol. 746, pp. 63–69, 2015.
- Young-Min Son, Da-Hye Jeong, Hwa-Jin Park, and Man-Hee Rhee, “The inhibitory activity of ginsenoside Rp4 in adenosine diphosphate-induced platelet aggregation,” Journal of Ginseng Research, 2016.
- Xiao-Hui Zhang, Shi-Yuan Zhou, Ru Feng, Ya-Zhe Wang, Yuan Kong, Yi Zhou, Jia-Min Zhang, Min Wang, Jing-Zhong Zhao, Qian-Ming Wang, Fei-Er Feng, Xiao-Lu Zhu, Feng-Rong Wang, Jing-Zhi Wang, Wei Han, Huan Chen, Lan-Ping Xu, Yan-Rong Liu, Kai-Yan Liu, and Xiao-Jun Huang, “Increased prostacyclin levels inhibit the aggregation and activation of platelets via the PI3K–AKT pathway in prolonged isolated thrombocytopenia after allogeneic hematopoietic stem cell transplantation,” Thrombosis Research, 2016.