Ginseng Berry Extract Prevents Atherogenesis via Anti-Inflammatory Action by Upregulating Phase II Gene Expression
Figure 3
KGBE inhibits the production of inflammatory mediators in HFD-fed ApoE−/− mice. (a–c, upper panels) Levels of TNF-α, IL-1β, and iNOS mRNAs were determined in the aortic tissues from mice fed NCD, HFD, and HFD supplemented with KGBE or KRGE for 16 weeks by RT-PCR. (a–c, lower panels) Levels of TNF-α, IL-1β, and NOx were determined in sera from mice using ELISA kits and a reductase-based Griess reaction kit. Data shown in graphs are the mean ± S.D. (). * and ** versus HFD.