Antidepressant-Like Activity of the Ethanolic Extract from Uncaria lanosa Wallich var. appendiculata Ridsd in the Forced Swimming Test and in the Tail Suspension Test in Mice

Table 5

Effects of UL_EtOH (0.125, 0.25, 0.5 g/kg, p.o.) and clorgyline (10 mg/kg, i.p.) for two weeks’ administration on MAO-A, MAO-B activity in mouse brain.

Group	MAO-A activity (% of mouse brain)	MAO-B activity (% of mouse brain)
Control	98.56±4.44	96.89±4.10
Clorgyline 10 mg/kg	45.05±8.02 **	102.41±5.50
ULEtOH 0.125 g/kg	107.31±14.21	103.86±7.46
ULEtOH 0.25 g/kg	80.97±7.20	107.70±5.50
ULEtOH 0.5 g/kg	49.84±7.02 **	105.94±3.99

Value were the mean ± SEM (𝑛=6). **𝑃<0.01 as compared with the control group (one-way ANOVA following by Bonferroni’s test).