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Evidence-Based Complementary and Alternative Medicine
Volume 2012 (2012), Article ID 498467, 10 pages
It Is Not Just Folklore: The Aqueous Extract of Mung Bean Coat Is Protective against Sepsis
1Laboratory of Emergency Medicine, The Feinstein Institute for Medical Research, 350 Community Drive, Manhasset, NY 11030, USA
2Department of Emergency Medicine, North Shore University Hospital, The Hofstra North Shore-LIJ School of Medicine at the Hofstra University, Manhasset, NY 11030, USA
Received 30 July 2012; Accepted 2 September 2012
Academic Editor: Andreas Sandner-Kiesling
Copyright © 2012 Shu Zhu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- D. C. Angus, W. T. Linde-Zwirble, J. Lidicker, G. Clermont, J. Carcillo, and M. R. Pinsky, “Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care,” Critical Care Medicine, vol. 29, no. 7, pp. 1303–1310, 2001.
- G. R. Bernard, J. L. Vincent, P. F. Laterre et al., “Efficacy and safety of recombinant human activated protein C for severe sepsis,” New England Journal of Medicine, vol. 344, no. 10, pp. 699–709, 2001.
- E. D. Chan and D. W. H. Riches, “IFN-γ + LPS induction of iNOS is modulated by ERK, JNK/SAPK, and p38mapk in a mouse macrophage cell line,” American Journal of Physiology, vol. 280, no. 3, pp. C441–C450, 2001.
- T. M. Wizemann, C. R. Gardner, J. D. Laskin et al., “Production of nitric oxide and peroxynitrite in the lung during acute endotoxemia,” Journal of Leukocyte Biology, vol. 56, no. 6, pp. 759–768, 1994.
- H. Wang, O. Bloom, M. Zhang et al., “HMG-1 as a late mediator of endotoxin lethality in mice,” Science, vol. 285, no. 5425, pp. 248–251, 1999.
- B. Lu, T. Nakamura, K. Inouye et al., “Novel role of PKR in inflammasome activation and HMGB1 release,” Nature, vol. 488, no. 7413, pp. 670–674, 2012.
- H. Yang, M. Ochani, J. Li et al., “Reversing established sepsis with antagonists of endogenous high-mobility group box 1,” Proceedings of the National Academy of Sciences of the United States of America, vol. 101, no. 1, pp. 296–301, 2004.
- H. Wang, H. Yang, C. J. Czura, A. E. Sama, and K. J. Tracey, “HMBG1 as a late mediator of lethal systemic inflammation,” American Journal of Respiratory and Critical Care Medicine, vol. 164, no. 10, pp. 1768–1773, 2001.
- S. Qin, H. Wang, R. Yuan et al., “Role of HMGB1 in apoptosis-mediated sepsis lethality,” Journal of Experimental Medicine, vol. 203, no. 7, pp. 1637–1642, 2006.
- H. Wang, S. Zhu, R. Zhou, W. Li, and A. E. Sama, “Therapeutic potential of HMGB1-targeting agents in sepsis.,” Expert Reviews in Molecular Medicine, vol. 10, p. e32, 2008.
- M. P. Fink, “Ethyl pyruvate: a novel anti-inflammatory agent,” Critical Care Medicine, vol. 31, supplement 1, pp. S51–S56, 2003.
- L. Ulloa, M. Ochani, H. Yang et al., “Ethyl pyruvate prevents lethality in mice with established lethal sepsis and systemic inflammation,” Proceedings of the National Academy of Sciences of the United States of America, vol. 99, no. 19, pp. 12351–12356, 2002.
- W. Li, J. Li, M. Ashok et al., “A cardiovascular drug rescues mice from lethal sepsis by selectively attenuating a late-acting proinflammatory mediator, high mobility group box 1,” Journal of Immunology, vol. 178, no. 6, pp. 3856–3864, 2007.
- W. Li, S. Zhu, J. Li et al., “A hepatic protein, fetuin-A, occupies a protective role in lethal systemic inflammation,” PLoS ONE, vol. 6, no. 2, Article ID e16945, 2011.
- H. Wang, H. Liao, M. Ochani et al., “Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis,” Nature Medicine, vol. 10, no. 11, pp. 1216–1221, 2004.
- S. Zhu, M. Ashok, J. Li et al., “Spermine protects mice against lethal sepsis partly by attenuating surrogate inflammatory markers,” Molecular Medicine, vol. 15, no. 7-8, pp. 275–282, 2009.
- D. Tang, R. Kang, W. Xiao et al., “Quercetin prevents LPS-induced high-mobility group box 1 release and proinflammatory function,” American Journal of Respiratory Cell and Molecular Biology, vol. 41, no. 6, pp. 651–660, 2009.
- B. Levine, N. Mizushima, and H. W. Virgin, “Autophagy in immunity and inflammation,” Nature, vol. 469, no. 7330, pp. 323–335, 2011.
- T. Shintani and D. J. Klionsky, “Autophagy in health and disease: a double-edged sword,” Science, vol. 306, no. 5698, pp. 990–995, 2004.
- J. Harris, S. A. De Haro, S. S. Master et al., “T helper 2 cytokines inhibit autophagic control of intracellular mycobacterium tuberculosis,” Immunity, vol. 27, no. 3, pp. 505–517, 2007.
- Y. Xu, C. Jagannath, X. D. Liu, A. Sharafkhaneh, K. E. Kolodziejska, and N. T. Eissa, “Toll-like receptor 4 is a sensor for autophagy associated with innate immunity,” Immunity, vol. 27, no. 1, pp. 135–144, 2007.
- Y. C. Hsieh, M. Athar, and I. H. Chaudry, “When apoptosis meets autophagy: deciding cell fate after trauma and sepsis,” Trends in Molecular Medicine, vol. 15, no. 3, pp. 129–138, 2009.
- W. Li, M. Ashok, J. Li, H. Yang, A. E. Sama, and H. Wang, “A major ingredient of green tea rescues mice from lethal sepsis partly by inhibiting HMGB1,” PLoS ONE, vol. 2, no. 11, Article ID e1153, 2007.
- W. Li, S. Zhu, J. Li et al., “EGCG stimulates autophagy and reduces cytoplasmic HMGB1 levels in endotoxin-stimulated macrophages,” Biochemical Pharmacology, vol. 81, no. 9, pp. 1152–1163, 2011.
- R. N. Adsule, S. S. Kadam, and D. K. Salunkhe, “Chemistry and technology of green gram (Vigna radiata [L.] Wilczek).,” Critical Reviews in Food Science and Nutrition, vol. 25, no. 1, pp. 73–105, 1986.
- I. M. Chung, M. A. Yeo, S. J. Kim, and H. I. Moon, “Protective effects of organic solvent fractions from the seeds of Vigna radiata L. wilczek against antioxidant mechanisms,” Human and Experimental Toxicology, vol. 30, no. 8, pp. 904–909, 2011.
- D. Cao, H. Li, J. Yi et al., “Antioxidant properties of the mung bean flavonoids on alleviating heat stress,” PLoS ONE, vol. 6, no. 6, Article ID e21071, 2011.
- H. Wang, W. Li, J. Li et al., “The aqueous extract of a popular herbal nutrient supplement, Angelica sinensis, protects mice against lethal endotoxemia and sepsis,” Journal of Nutrition, vol. 136, no. 2, pp. 360–365, 2006.
- B. Rendon-Mitchell, M. Ochani, J. Li et al., “IFN-γ induces high mobility group box 1 protein release partly through a TNF-dependent mechanism,” Journal of Immunology, vol. 170, no. 7, pp. 3890–3897, 2003.
- G. Chen, J. Li, M. Ochani et al., “Bacterial endotoxin stimulates macrophages to release HMGB1 partly through CD14- and TNF-dependent mechanisms,” Journal of Leukocyte Biology, vol. 76, no. 5, pp. 994–1001, 2004.
- D. J. Klionsky, F. C. Abdalla, H. Abeliovich, et al., “Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes,” Autophagy, vol. 4, no. 2, pp. 151–175, 2008.
- W. J. Hubbard, M. Choudhry, M. G. Schwacha et al., “Cecal ligation and puncture,” Shock, vol. 24, supplement 1, pp. 52–57, 2005.
- W. Li, S. Zhu, Y. Zhang et al., “Use of animal model of sepsis to evaluate novel herbal therapies,” Journal of Visualized Experiments, no. 62, p. 3926, 2012.
- X. Peng, Z. Zheng, K. W. Cheng et al., “Inhibitory effect of mung bean extract and its constituents vitexin and isovitexin on the formation of advanced glycation endproducts,” Food Chemistry, vol. 106, no. 2, pp. 475–481, 2008.
- R. T. Eastman and D. A. Fidock, “Artemisinin-based combination therapies: a vital tool in efforts to eliminate malaria,” Nature Reviews Microbiology, vol. 7, no. 12, pp. 864–874, 2009.
- L. Smeding, H. Leong-Poi, P. Hu, et al., “Salutary effect of resveratrol on sepsis-induced myocardial depression,” Critical Care Medicine, vol. 40, no. 6, pp. 1896–1907, 2012.
- B. Jian, S. Yang, I. H. Chaudry, and R. Raju, “Resveratrol improves cardiac contractility following trauma-hemorrhage by modulating Sirt1,” Molecular Medicine, vol. 18, no. 1, pp. 209–214, 2012.
- K. Hayakawa, K. Mishima, K. Irie et al., “Cannabidiol prevents a post-ischemic injury progressively induced by cerebral ischemia via a high-mobility group box1-inhibiting mechanism,” Neuropharmacology, vol. 55, no. 8, pp. 1280–1286, 2008.
- K. R. Kasten, J. Tschöp, M. H. Tschöp, and C. C. Caldwell, “The cannabinoid 2 receptor as a potential therapeutic target for sepsis,” Endocrine, Metabolic and Immune Disorders-Drug Targets, vol. 10, no. 3, pp. 224–234, 2010.
- J. Tschöp, K. R. Kasten, R. Nogueiras et al., “The cannabinoid receptor 2 is critical for the host response to sepsis,” Journal of Immunology, vol. 183, no. 1, pp. 499–505, 2009.
- D. Tang, R. Kang, K. M. Livesey et al., “Endogenous HMGB1 regulates autophagy,” Journal of Cell Biology, vol. 190, no. 5, pp. 881–892, 2010.
- R. Kang, K. M. Livesey, H. J. Zeh, M. T. Lotze, and D. Tang, “HMGB1: a novel Beclin 1-binding protein active in autophagy,” Autophagy, vol. 6, no. 8, pp. 1209–1211, 2010.
- S. Zhu, J. Li, W. Li, et al., “Mung Bean (Vigna Radiata) Extract is Protective against Lethal Sepsis in Mice,” Shock, vol. 37, supplement 1, no. 6, pp. 25–26, 2012.