Neuroprotective Effects of San-Huang-Xie-Xin-Tang in the MPP⁺/MPTP Models of Parkinson’s Disease In Vitro and In Vivo

Figure 1

Effects of SHXT on MPP⁺-induced cell death of primary mesencephalic neurons. Cells were treated with SHXT (25–75 μg/mL) 1 h prior to MPP⁺ (100 μM) addition for 48 h. (a) Cell viability was determined by MTT assay. (b) Cytotoxicity was measured by LDH assay. Bars represent the mean ± S.E.M. from six independent experiments. ^##𝑃<0.01, ^###𝑃<0.001 versus control (without any treatment), *𝑃<0.05, **𝑃<0.01 versus MPP⁺ only.

(a)

(b)