Figure 5: ISCADOR reduces cell motility and invasiveness in human and mouse GBM cell lines. (a) Boyden chamber migration assays. The cells were treated for 24 h with ISCADOR P, M, or Q (100 μg/mL). 20.000 treated cells were seeded in upper parts of Boyden chambers. Migrated cells were counted 21 h later ( for ISCADOR P, for ISCADOR M, for ISCADOR Q, SEM). (b) Scratch assay. The cells were seeded and treated as in (a) 24 h after treatment a scratch was set and migration of cells were documented photographically every 24 h. For better visualization, migration borders were marked with black lines (, one representative experiment is shown). (c) Boyden chamber matrigel invasion assay. The cells were treated as in (a) (, SEM).