Depression, Comorbidities, and Prescriptions of Antidepressants in a German Network of GPs and Specialists with Subspecialisation in Anthroposophic Medicine: A Longitudinal Observational Study

Table 4

Likelihood of being prescribed any antidepressant medication by co-morbidity (𝑛=2444).

Co-morbid condition	Patients who were prescribed an antidepressant		Likelihood of being prescribed antidepressant
	Patients with co-morbidity	Patients without co-morbidity	Unadjusted OR	Model 1; Adjusted OR^1; (95% CI)	Model 2; Adjusted OR^1; (95% CI)
	𝑛/𝑁 (%)	𝑛/𝑁 (%)
Coronary heart disease	84/202 (41.6)	749/2242 (33.4)	1.419; (1.058–1.903)*	1.028; (0.753–1.404)	1.191; (0.864–1.643)
Cerebrovascular disease	56/99 (56.6)	777/2345 (33.1)	2.628; (1.750–3.947)*	1.781; (1.159–2.739)*	1.762; (1.124–2.762)*
Diabetes mellitus	82/174 (47.1)	751/2270 (33.1)	1.803; (1.322–2.459)*	1.342; (0.968–1.860)	1.317; (0.936–1.855)
Cancer	108/351 (30.8)	725/2093 (34.6)	0.829; (0.657–1.070)	0.652; (0.505–0.842)*	0.745; (0.572–0.969)*
Congestive heart failure	59/113 (52.2)	774/2331 (33.2)	2.198; (1.504–3.211)*	1.431; (0.951–2.154)	1.652; (1.082–2.521)*
Chronic obstructive Pulmonary disease	34/68 (50.0)	799/2376 (33.6)	1.974; (1.218–3.199)*	1.612; (0.986–2.638)	1.950; (1.188–3.200)*
Any comorbidity	267/708 (37.7)	566/1736 (32.6)	1.252; (1.043–1.502)*	0.878; (0.709–1.086)	1.007; (0.807–1.257)

¹Odds ratio for patients who had a co-morbidity compared to patients who did not have co-morbidity.
Model 1: adjusted for patient age and gender.
Model 2: adjusted for patient age and gender, as well as for physician specialisation and type of depression.