Epicatechin Used in the Treatment of Intestinal Inflammatory Disease: An Analysis by Experimental Models

Table 1

Macroscopic and microscopic scores of the different groups submitted to the acute model.

	Non-colitic	TNBS control	EC 5	EC 10	EC 25	EC 50	Sulfa.
Macroscopic score	0*	9 (1.25)	8 (1)	7 (1)*	7.5 (1)	7 (0.5)*	8 (1.5)
Microscopic score	0*	19 (1.5)	18 (1.0)	15 (1.5)*	18 (3.5)	16 (2.0)	16 (1.0)

Results expressed as median (interquartile range). Kruskal-Wallis-Mann-Whitney, *P < 0.05 in relation to the check. n = 5–8. EC 5 to 50: Epicatechin, doses 5 to 50 mg/kg; Sulfa.: Sulfasalazine.