Research Article
A Systems Biology Approach to Uncovering Pharmacological Synergy in Herbal Medicines with Applications to Cardiovascular Disease
Table 2
Comparison of molecular properties between RSM, RAM, RPL, and ROJ.
| | Index | RSM (mean SD) | RAM (mean SD) | ROJ (mean SD) | RPL (mean SD) | | Total compounds | Active compounds | Total compounds | Active compounds | Total compounds | Active compounds | Total compounds | Active compounds |
| | nHDon | 2.09
(2.69) | 1.95
(3.88) | 4.05
(2.86) | 3.89
(2.77) | 3.22
(3.23) | 2.68
(1.49) | 5.00
(4.65) | 3.42
(2.19) | | nHAcc | 4.23
(4.47) | 5.19
(6.78) | 7.51
(4.70) | 7.91
(4.32) | 6.72
(6.22) | 6.58
(2.46) | 8.50
(7.62) | 6.42
(3.70) | | MLogP | 2.45
(2.61) | 2.10
(2.28) | 0.75
(2.59) | 1.18
(2.60) | 2.12
(2.48) | 1.61
(0.91) | 1.28
(3.38) | 1.44
(2.57) | | MW | 310.37 (156.93) | 343.28
(219.76) | 411.00 (232.39) | 438.31
(169.88) | 428.72 (262.11) | 373.42
(120.83) | 484.18 (286.37) | 379.77
(92.05) | | RBN | 3.66
(5.17) | 2.09
(4.99) | 5.17
(3.68) | 5.02
(3.42) | 4.99
(4.81) | 3.26
(1.45) | 6.58
(6.02) | 4.08
(3.96) | | nCIC | 2.74
(1.73) | 3.72
(1.35) | 3.59
(2.66) | 4.14
(1.84) | 4.05
(3.01) | 3.74
(1.52) | 3.89 (2.6971) | 3.58
(1.38) | | Hy | 0.56
(2.00) | 0.38
(2.79) | 1.92
(2.06) | 1.68
(1.95) | 1.13
(2.13) | 0.74
(0.97) | 2.46
(3.28) | 1.28
(1.61) | | TPSA (Tot) | 73.61
(76.27) | 86.86
(114.01) | 120.61
(72.73) | 123.18
(69.35) | 102.76
(92.12) | 100.13
(35.49) | 142.01
(125.68) | 106.28
(59.74) |
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*RSM (Radix Salviae Miltiorrhiza), RAM (Radix Astragali Mongolici), RPL (Radix Puerariae lobatae), and ROJ (Radix Ophiopogonis Japonici).
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