Quercetin Protects against Cadmium-Induced Renal Uric Acid Transport System Alteration and Lipid Metabolism Disorder in Rats

Figure 6

Effects of a 4-week treatment of CdCl₂ and coadministration of quercetin on expression of RST (a), OAT1 (b), MRP4 (c), and ABCG2 (d) at mRNA levels and activity of Na⁺-K⁺-ATPase (e) in renal cortex of rats. The mRNA levels were normalized by GAPDH. Values are mean ± SEM of 𝑛=4-6 in each group. 𝑃 value CdCl₂ versus control at ⁺ < 0.05, ⁺⁺ < 0.01, and ⁺⁺⁺ < 0.001; treatment versus CdCl₂ at *<0.05 and **<0.01 for LSD post hoc test.

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