Quercetin Protects against Cadmium-Induced Renal Uric Acid Transport System Alteration and Lipid Metabolism Disorder in Rats

Figure 9

Effects of a 4-week treatment of CdCl₂ and coadministration of quercetin on expression of OCTN2 (a), CPT1 (b), AMPK (c), PPARα (d), SREBP-1 (e), PGC-1β (f) at mRNA levels, and OCTN2 (g) and CPT1 (h) at protein levels in renal cortex of rats. The mRNA levels or protein levels were normalized by GAPDH, respectively. Values are mean ± SEM of 𝑛=4-6 in each group. 𝑃 value CdCl₂ versus control at ⁺ < 0.05, ⁺⁺ < 0.01, and ⁺⁺⁺<0.001; treatment versus CdCl₂ at *<0.05, **<0.01, and ***<0.001 for LSD post hoc test.

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