Ferulsinaic Acid Modulates SOD, GSH, and Antioxidant Enzymes in Diabetic Kidney

Figure 1

8-Hydroxy-2′-deoxyguanosine levels in the urine (a) and renal cortex (b) of rats. Urinary and renal cortex 8-OHdG levels in diabetic rats were significantly attenuated in a dose-dependent manner after FA administration. Data are expressed as the means ± SD. DN indicates diabetes untreated group; FA1, FA2, and FA3, diabetic rats treated with low dose (5 ng/kg) of FA (DN + FA1), middle dose (50 ng/kg) of FA (DN + FA2), and high dose (500 ng/kg) of FA (DN + FA3), respectively. *𝑃<0.05 versus normal control group, **𝑃<0.05 versus diabetes untreated group.

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