Early Blockade of TLRs MyD88-Dependent Pathway May Reduce Secondary Spinal Cord Injury in the Rats
Figure 5
NeuN-positive cells in the spinal cord at 7 d and 14 d post injury. (a) and (b) are the representative pictures of NeuN immunohistochemical staining in CP group and MIP group, respectively, at 14 d. The areas of a1 and b1, are the first 1000 μm from the lesion border indicated by initiating appearance of NeuN positive cells, while a2 and b2 are second 1000 μm adjacent to a1 and b1 respectively; and A1, A2, B1, and B2, are the magnifications of a1, a2, b1, and b2 respectively. (c) As compared to the CP group, the number of neurons is significantly higher in the MIP group in the first 1000 μm and the second 1000 μm at 7 d after injury (*), and at 14 d there was an obvious difference between CP and MIP groups in the first 1000 μm while there was no difference between these two groups in the second 1000 μm.
