Inhibition of Advanced Glycation End-Product Formation by Origanum majorana L. In Vitro and in Streptozotocin-Induced Diabetic Rats

Table 6

Effect of OM on the glycation of tail tendon collagen.

Treatment	Total collagen; (mg/100 mg tendon)	Pepsin digested; (mg/100 mg tendon)	Collagen glycation; (𝜇g glucose/mg collagen)	Fluorescence; (AU/mg collagen)
Normal	37.6±1.57	3.46±0.039	2.98±0.38	2.85±0.051
Diabetic	75.9±1.43	1.47±0.075	14.57±0.17	24.63±0.73
Diabetic + OM	44.3 ± 2.19^ab	2.54 ± 0.019^ab	9.32 ± 0.58^ab	16.80 ± 0.60^ab
Diabetic + Glibenclamide	47.1 ± 1.56^ab	2.19 ± 0.026^ab	8.09 ± 0.52^ab	17.21 ± 0.84^ab

Data as expressed as ±SD; 𝑛=5; ^aversus normal control; ^bversus diabetic control.