Review Article
From Omics to Drug Metabolism and High Content Screen of Natural Product in Zebrafish: A New Model for Discovery of Neuroactive Compound
Table 3
Potential marker genes for epilepsy.
| Function | Gene | Assessment method | References |
| Transcription factor | c-Fos | Immunohistochemistry, In situ hybridization, real-time PCR | [85] | c-Jun | Electrophoretic mobility-shift assay | [86] | CREB | Real-time PCR, northern blot | [87] | Zac 1 | Immunohistochemistry, In situ hybridization | [88] | Receptor | NMDAR1 | Immunohistochemistry, Western blot | [89] | GABA(A)-receptor delta | Immunohistochemistry | [81] | Ion channel | Kv1.2 and Kv4.2 | In situ hybridization | [90] | Transporter | GLUT1 and GLUT3 | In situ hybridization, Western blot | [91] |
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