From Omics to Drug Metabolism and High Content Screen of Natural Product in Zebrafish: A New Model for Discovery of Neuroactive Compound

Table 4

Potential biomarkers for human heart disease.

Gene	Function	Assessment method	Associated cardiovascular disease
Troponin T	Myocardial contraction	ELISA	Congestive heart failure [96, 97]
Heart fatty acid binding protein	Carrier proteins for fatty acids and other lipophilic substances, such as eicosanoids and retinoids	ELISA	Congestive heart failure [96, 97]
Myosin light chain-I	Myocardial contraction	ELISA	Congestive heart failure [96, 100]
Creatine kinase MB	Energy metabolism	ELISA	Congestive heart failure [96]
Cardiotrophin-1	Response to stress and humoral factors such as angiotensin II	ELISA	Hypertension [98]
Endothelin-1	Potent endothelium-derived vasoconstrictor peptide	Radioimmunoassay	Heart failure [99]