Research Article

Inhibitory Activities of Zygophyllum album: A Natural Weight-Lowering Plant on Key Enzymes in High-Fat Diet-Fed Rats

Table 3

Total cholesterol (T-Ch), LDL cholesterol (LDL-c), HDL cholesterol (HDL-c); and triglycerides (TGs) in serum and liver of HFD-fed rats treated with EZA.

Groups Control HFDHFD + fluv.HFD + EZA

Serum (mmol/L)

T-Ch 1.67 ± 0.20 2.72 ± 0.14* 1.77 ± 0.1*# 1.74 ± 0.1*#
TGs 0.96 ± 0.21 1.4 ± 0.16* 0.96 ± 0.07*# 0.96 ± 0.04*#
LDL-c 0.47 ± 0.22 1.61 ± 0.16* 0.49 ± 0.15*# 0.53 ± 0.03*#
HDL-c 1.02 ± 0.09 0.82 ± 0.04* 1.04 ± 0.07# 1.05 ± 0.06#

Liver (mg/100 mg WT)

T-Ch 1.08 ± 0.05 2.45 ± 0.15* 1.22 ± 0.02*# 1.27 ± 0.05*#
TGs 0.63 ± 0.07 1.45 ± 0.11* 0.72 ± 0.06*# 0.77 ± 0.04*#
LDL-c 0.53 ± 0.03 1.78 ± 0.12* 0.45 ± 0.04*# 0.48 ± 0.03 *#
HDL-c 0.44 ± 0.02 0.38 ± 0.01* 0.49 ± 0.02*# 0.51 ± 0.02*#

WT: wet tissue. Values are given as mean ± SD for groups of 8 animals each. Values are statistically presented as follows: * significant differences compared to controls. # < 0.05 significant differences compared to HFD rats.