Inhibitory Activities of Zygophyllum album: A Natural Weight-Lowering Plant on Key Enzymes in High-Fat Diet-Fed Rats
Table 5
Liver profile indices (AST, ALT, ALP, GGT, CPK, and T-Bili) and kidney parameters (creatinine, urea, and uric acid) of control and experimental groups of rats. Values are given as mean ± SD for groups of 8 animals each.
Control
HFD
HFD + fluv.
HFD + EZA
Liver function
AST (UI/L)
106.7 ± 11.52
194.42 ± 7.63*
128 ± 6.54*#
123 ± 4.37*#
ALT (UI/L)
60.57 ± 8.88
90.85 ± 5.75*
71 ± 9.14*#
66.28 ± 5.4#
PAL (UI/L)
281.28 ± 42.8
627.42 ± 83.73*
365.28 ± 78.39*#
308.28 ± 61.54#
GGT (UI/L)
3.42 ± 0.53
6.71 ± 0.75*
4.57 ± 0.74*#
4.5 ± 1.04*#
CPK (UI/L)
3128 ± 193
4147 ± 198*
3317 ± 185#
3439 ± 170*#
T-Bili (μmol/L)
1.66 ± 0.21
2.51 ± 0.24*
1.6 ± 0.33#
1.64 ± 0.26#
Kidney function
Urea (mmol/L)
6.35 ± 0.41
8.47 ± 0.27*
6.41 ± 0.37#
6.79 ± 0.47#
Uric acid (μmol/L)
62.73 ± 6.74
72.85 ± 6.6*
64.77 ± 7.46#
62.37 ± 5.14#
Creatinine (μmol/L)
44.7 ± 0.94
64.38 ± 3.56*
41.3 ± 1.7#
46.4 ± 1.88#
Values are statistically presented as follows: * significant differences compared to controls. # < 0.05 significant differences compared to HFD rats.
