Anxiolytic Effects of Flavonoids in Animal Models of Posttraumatic Stress Disorder

Figure 1

The effects of repeated treatment with Ser or flavonoids on freezing behavior in mice after exposure to electric foot-shocks. The total cumulative freezing time was determined on day 3, 8, and 15. Daily administrations of Ser or flavonoids were started from the first day of training session. Data are presented as mean ± SEM (𝑛=10). *𝑃<0.05, **𝑃<0.01 compared with foot shock (−) group; ^#𝑃<0.05, ^##𝑃<0.01 compared with saline-treated foot shock (+) group (ANOVA followed by Dunnett’s 𝑡-test).

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