Protective Effect of Proanthocyanidin against Diabetic Oxidative Stress

Figure 5

Hepatic SREBP-1, SREBP-2, and PPARα protein levels in mouse model of type 2 diabetes. (a) SREBP-1, (b) SREBP-2, (c) PPARα. The results are expressed as the mean ± SEM. Significance: ^a𝑃<0.05, ^b𝑃<0.01, ^c𝑃<0.001 versus db/db mice treated with vehicle. m/m, nondiabetic misty mice; Veh, db/db vehicle-treated mice; P, db/db mice treated with polymeric proanthocyanidin (10 mg/kg body weight); O, db/db mice treated with oligomeric proanthocyanidin (10 mg/kg body weight).

(a)

(b)

(c)