Protective Effect of Proanthocyanidin against Diabetic Oxidative Stress

Figure 6

Hepatic NF-κB, IκB-α, COX-2, and iNOS protein levels in mouse model of type 2 diabetes. (a) NF-κB, (b) IκB-α, (c) COX-2, (d) iNOS. The results are expressed as the mean ± SEM. Significance: ^a𝑃<0.05, ^b𝑃<0.01, ^c𝑃<0.001 versus db/db mice treated with vehicle. m/m, nondiabetic misty mice; Veh, db/db vehicle-treated mice; P, db/db mice treated with polymeric proanthocyanidin (10 mg/kg body weight); O, db/db mice treated with oligomeric proanthocyanidin (10 mg/kg body weight).

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